At doses higher than the advisable dose variety, adverse reactions ended up comparable to those in depth in Table one beneath but commonly had been described a lot more commonly.
The most major interactions can come from combining PDE5 inhibitors with nitrates or compounds containing nitrates. Several scientific studies, like a 2018 research, see that applying PDE5 inhibitors with nitrates could cause a existence threatening fall in blood pressure level.
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VIAGRA was proven to potentiate the hypotensive outcomes of nitrates and its administration in clients who use nitric oxide donors which include organic and natural nitrates or organic and natural nitrites in any kind is therefore contraindicated [see CONTRAINDICATIONS, DRUG INTERACTIONS, and CLINICAL PHARMACOLOGY].